Health Concerns of the Ingredient:
Overall Hazard
Allergies & immunotoxicity
About CYCLOTETRASILOXANE: Cyclotetrasiloxane is a cyclic dimethyl polysiloxane.
Function(s): Hair Conditioning Agent; Skin-Conditioning Agent - Emollient; Solvent; SKIN CONDITIONING
Synoym(s): CYCLOTETRASILOXANE, OCTAMETHYL; CYCLOTETRASILOXANE, OCTAMETHYL-; DECAMETHYLCYCLOTETRASILOXANE; HEXANETHYLCYCLOTRISILOXANE; OCTAMETHYL CYCLOTETRASILOXANE; OCTAMETHYL- CYCLOTETRASILOXANE; OCTAMETHYLCYCLOTETRASILOXANE
Endocrine disruption
| Concern |
Reference |
| Human endocrine disruptor - strong evidence | European Commission on Endocrine Disruption |
Developmental/reproductive toxicity
| Concern |
Reference |
| Limited evidence of developmental toxicity | European Union - Classification & Labelling |
Organ system toxicity (non-reproductive)
| Concern |
Reference |
| Classified as a high human health priority | Environment Canada Domestic Substance List |
| Classified as expected to be toxic or harmful | Environment Canada Domestic Substance List |
Persistence and bioaccumulation
| Concern |
Reference |
| Persistent or bioaccumulative and moderate to high toxicity concern in humans | Environment Canada Domestic Substance List |
| Persistent, bioaccumulative in wildlife | Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET) |
Ecotoxicology
| Concern |
Reference |
| Wildlife and environmental toxicity | European Union - Classification & Labelling |
| Suspected to be an environmental toxin and be persistent or bioaccumulative | Environment Canada Domestic Substance List |
| Suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Data gaps
| Concern |
Reference |
| 120 studies in PubMed science library may include information on the toxicity of this chemical see search results -> | NLM PubMed |
Data Sources
| CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC. |
| CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP. |
| EC (Environment Canada). 1994. Accelerated Reduction/Elimination of Toxics (ARET). ARET substance list of persistent, bioaccumulative and toxic chemicals. |
| EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| EU (European Union)- Strategy for Endocrine Disrupters 2007. Commision on endocrin disruption requested by the European Parliament in 1998. |
| NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov. |
Products Containing the Ingredient
About the ratings
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any.
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