CYCLOMETHICONE
About the ratings
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any.
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Function/use(s): ANTISTATIC; EMOLLIENT; HAIR CONDITIONING; HUMECTANT; SOLVENT; VISCOSITY CONTROLLING
About CYCLOMETHICONE: Cyclomethicone is a silicon-based cyclic compound; may be associated with environmental toxicity.
Synonym(s): CYCLOPENTASILOXANE, DECAMETHYL; DECAMETHYLCYCLOMETHICONE; CYCLIC DIMETHYLSILOXANE PENTAMER; CYCLOPOLYDIMETHYLSILOXANE; DECAMETHYLCYCLOPENTASILOXANE; DEKAMETHYLCYKLOPENTASILOXAN (CZECH) ; DIMETHYLCYCLOPOLYSILOXANE; DIMETHYLSILOXANE PENTAMER; DOW CORNING 344; DOW CORNING 344 FLUID; DOW CORNING 345
Persistence and bioaccumulation |
| type of concern |
product conditions |
reference |
|---|
| Persistent or bioaccumulative and moderate to high toxicity concern in humans |
|
Environment Canada Domestic Substance List |
| Persistent, bioaccumulative in wildlife |
|
Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET) |
| show more |
| Not suspected to be bioaccumulative |
|
Environment Canada Domestic Substance List | |
Organ system toxicity (non-reproductive) |
| type of concern |
product conditions |
reference |
|---|
| Classified as medium human health priority |
|
Environment Canada Domestic Substance List |
| Classified as expected to be toxic or harmful |
|
Environment Canada Domestic Substance List |
Ecotoxicology |
| type of concern |
product conditions |
reference |
|---|
| Suspected to be an environmental toxin |
|
Environment Canada Domestic Substance List |
Data gaps |
| type of concern |
product conditions |
reference |
|---|
| Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product |
|
Cosmetic Ingredient Review Assessments |
| 58 studies in PubMed science library may include information on the toxicity of this chemical
see search results ->
|
|
PubMed |
Government, industry, academic studies and classifications |
| government/industry list/academic study |
appears on list as |
classification(s) |
| Cosmetic Ingredient Review Assessments | CYCLOMETHICONE | QQQ01,QQQ11; M- |
| Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET) | CYCLOSILOXANES, DIME | Identified as a priority action PBT under Environment Canada's July 2006 assessment |
| Environment Canada Domestic Substance List | CYCLOSILOXANES, DI-ME | Y-Categorization,Y-Human health,Moderate-Health Priority,Y-Persistent,,Y-AquaticTox,,,, |
Other RTECS® classifications [shown for informational purposes only] |
| government/industry list/academic study |
appears on list as |
classification(s) |
| RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986 | CYCLOMETHICONE | • sense organ - Primary eye irritant (rabbit )
• skin - Primary skin irritant (rabbit )
|
| RTECS®- National Technical Information Service 0101 | CYCLOMETHICONE | • liver - Changes in liver weight (rat TDLo)
• biochemical - Hepatic microsomal mixed oxidase (dealkylation, hydroxylation, etc.) (rat TDLo)
• liver - Other changes (rat TDLo)
|
references |
| government/industry list/academic study
| reference
|
| Cosmetic Ingredient Review Assessments | CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC. |
| Canada PBTs - Accelerated Reduction/Elimination of Toxics (ARET) | EC (Environment Canada). 1994. Accelerated Reduction/Elimination of Toxics (ARET). ARET substance list of persistent, bioaccumulative and toxic chemicals. |
| Environment Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J 1986 [shown for informational purposes only] | RTECS®- "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 -,1234,1986 |
| RTECS®- National Technical Information Service 0101 [shown for informational purposes only] | RTECS®- National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. OTS0590101 |
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