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COPPER GLUCONATE


image source: PubChem
Health Concerns of the Ingredient:
Overall Hazard
 
 
Cancer
 
 
Developmental &
reproductive toxicity
 
 
Allergies & immunotoxicity
 
 
Use restrictions
 
 
Other HIGH concerns: Persistence and bioaccumulation; Other MODERATE concerns: Organ system toxicity (non-reproductive); Other LOW concerns: Ecotoxicology

About COPPER GLUCONATE: Copper Gluconate is a copper salt of gluconic acid.

Function(s): Not Reported; SKIN CONDITIONING; SKIN PROTECTING

Synonym(s): BIS (D-GLUCONATO) - COPPER; BIS (D-GLUCONATO) COPPER; COPPER DI-D-GLUCONATE; COPPER SALT GLUCONIC ACID; COPPER, BIS (D-GLUCONATO) -; COPPER, BIS (D-GLUCONATO-.KAPPA.O1,.KAPPA.O2) -; COPPER, BIS (DGLUCONATOO1,O2) ; CUPRIC GLUCONATE; GLUCONIC ACID, COPPER SALT; CHELATES OF COPPER GLUCONATE; COPPER (II) GLUCONATE

Persistence and bioaccumulation

Concern Reference
Persistent, bioaccumulative in wildlifeCanada PBTs - Accelerated Reduction/Elimination of Toxics (ARET)
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

Concern Reference
Classified as expected to be toxic or harmfulEnvironment Canada Domestic Substance List
Limited evidence of kidney toxicityMerck & Co
Limited evidence of respiratory toxicityCalifornia EPA, Office of Environmental Health Hazard Assessment
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)EPA Toxic Release Inventory PBTs

Ecotoxicology

Concern Reference
Suspected to be an environmental toxin and be persistent or bioaccumulativeEnvironment Canada Domestic Substance List
Suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

Concern Reference
30 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Multiple, additive exposure sources

Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Data Sources

California EPA, Office of Environmental Health Hazard Assessment. Acute Reference Exposure Levels (RELs), Averaging Times, and Toxicologic Endpoints. Includes all Acute Reference Exposure Levels (ARELs) developed by OEHHA through May 2000http://www.oehha.org/air/acute_rels/allAcRELs.html, California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document
EC (Environment Canada). 1994. Accelerated Reduction/Elimination of Toxics (ARET). ARET substance list of persistent, bioaccumulative and toxic chemicals.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Merck & Co. The Merck Manual of Diagnosis and Therapy. TABLE 226-1. Common Nephrotoxic Agents http://www.merck.com/pubs/mmanual/tables/226tb1.htm
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer