CARNITINE || Skin Deep® Cosmetics Database | Environmental Working Group

CARNITINE

Score	Data: Fair
CAS	541-15-1
body firming lotion (12 products)
anti-aging (4 products)
moisturizer (2 products)
eye drops/ artificial tears (2 products)
facial moisturizer/ treatment (2 products)
Show all 22 products that contain CARNITINE.
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CARNITINE

image source: PubChem

Health concerns of ingredient
About the ratings
Cancer	no information
Developmental & reproductive toxicity	no information
Allergies & immunotoxicity	no information
Use restrictions	no information
Contamination concerns: none
Other LOW concerns: Data gaps

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

Function/use(s): Antistatic Agent; Hair Conditioning Agent; Skin-Conditioning Agent - Miscellaneous;Surfactant - Cleansing Agent; Surfactant - Foam Booster; Viscosity Increasing Agent - Aqueous; FOAM BOOSTING; SKIN CONDITIONING; VISCOSITY CONTROLLING

Synonym(s): LEVOCARNITINE; (+) -CARNITINE; (+) -D-CARNITINE; (+-) -CARNITINE; (-) -CARNITINE; (-) -L-CARNITINE; (R) -CARNITINE; D- (+) -CARNITINE; D-CARNITINE; DL-CARNITINE; GAMMA-TRIMETHYL-BETA-HYDROXYBUTYROBETAINE

Data gaps
type of concern	product conditions	reference
Not assessed for safety in cosmetics by industry panel
11,159 studies in PubMed science library may include information on the toxicity of this chemical see search results ->		PubMed

Multiple, additive exposure sources
type of concern	product conditions	reference
Designated as safe for general or specific, limited use in food		FDA Everything Added to Food

Government, industry, academic studies and classifications
government/industry list/academic study	appears on list as	classification(s)
FDA Everything Added to Food	L-CARNITINE	• ASP

Other RTECS® classifications [shown for informational purposes only]
government/industry list/academic study	appears on list as	classification(s)
RTECS^®- Acta Biologica et Medica Germanica 1976	CARNITINE	• gastrointestinal - Changes in structure or function of salivary glands (mouse LD50) • brain, nervous system, or behavioral effect - Convulsions or effect on seizure threshold (mouse LD50) • sense organ - Lacrimation (mouse LD50)
RTECS^®- Chemico-Biological Interactions 2004	CARNITINE	• biochemical - Effect on mitochondrial function (rat TDLo) • cardiovascular - Other changes (rat TDLo)
RTECS^®- Farmakologiya i Toksikologiya (Moscow) 1992	CARNITINE	• biochemical - Other carbohydrates (mouse TDLo) • liver - Other changes (mouse TDLo)
RTECS^®- Gekkan Yakuji 1967	CARNITINE	• broad systemic - Broad systemic toxicity (mouse LD50)
RTECS^®- Psychopharmacology (Berlin) 2004	CARNITINE	• brain, nervous system, or behavioral effect - Changes in psychophysiological tests (woman TDLo)
RTECS^®- Toxicology 2003	CARNITINE	• blood - Changes in leucocyte (WBC) count (mouse TDLo) • endocrine system - Changes in spleen weight (mouse TDLo) • biochemical - Effect on cyclic nucleotides (mouse TDLo)

references
government/industry list/academic study	reference
FDA Everything Added to Food	FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
RTECS^®- Acta Biologica et Medica Germanica 1976 [shown for informational purposes only]	RTECS^®- Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. 35,645,1976
RTECS^®- Chemico-Biological Interactions 2004 [shown for informational purposes only]	RTECS^®- Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- 148,11,2004
RTECS^®- Farmakologiya i Toksikologiya (Moscow) 1992 [shown for informational purposes only]	RTECS^®- Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- 55,35,1992
RTECS^®- Gekkan Yakuji 1967 [shown for informational purposes only]	RTECS^®- Gekkan Yakuji. Pharmaceuticals Monthly. (Yakugyo Jihosha, Inaoka Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan) V.1- 1959- 9,759,1967
RTECS^®- Psychopharmacology (Berlin) 2004 [shown for informational purposes only]	RTECS^®- Psychopharmacology (Berlin). (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.47- 1976- 175,84,2004
RTECS^®- Toxicology 2003 [shown for informational purposes only]	RTECS^®- Toxicology. (Elsevier Scientific Pub. Ireland, Ltd., POB 85, Limerick, Ireland) V.1- 1973- 187,171,2003