Health Concerns of the Ingredient:
Overall Hazard
Developmental &
reproductive toxicity
Allergies & immunotoxicity
About AZELAIC ACID: Azelaic Acid is a dicarboxylic acid.
Function(s): Fragrance Ingredient; pH Adjuster; BUFFERING; MASKING
Synoym(s): 1,7-DICARBOXYHEPTANE; 1,7-HEPTANEDICARBOXYLIC ACID; ANCHOIC ACID; LEPARGYLIC ACID; NONANEDIOIC ACID; 1,7-HEPTANEDICARBOXYLIC ACID; ANCHOIC ACID; AZELAIC ACID, TECHNICAL GRADE; EMEROX 1110; EMEROX 1144; HEPTANEDICARBOXYLIC ACID
Use restrictions
| Concern |
Reference |
|---|
| Determined safe for use in cosmetics, subject to concentration or use limitations - Distinction between safe conc in leave-on and rinse-off (only for products that are intended to be left on the skin) | Cosmetic Ingredient Review Assessments |
Cancer
| Concern |
Reference |
|---|
| Not likely to be carcinogenic in humans | EPA Water Disinfection By-Products Carcinogenicity |
Data gaps
| Concern |
Reference |
|---|
| 467 studies in PubMed science library may include information on the toxicity of this chemical see search results -> | NLM PubMed |
Organ system toxicity (non-reproductive)
| Concern |
Reference |
|---|
| Classified as not expected to be potentially toxic or harmful | Environment Canada Domestic Substance List |
Persistence and bioaccumulation
| Concern |
Reference |
|---|
| Not suspected to be persistent | Environment Canada Domestic Substance List |
| Not suspected to be bioaccumulative | Environment Canada Domestic Substance List |
Ecotoxicology
| Concern |
Reference |
|---|
| Not suspected to be an environmental toxin | Environment Canada Domestic Substance List |
Data Sources
| CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC. |
| EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| EPA (U.S. Environmental Protection Agency). 2006. EPA Water Disinfection By-Products with Carcinogenicity Estimates. Last updated: 10 April 2006. |
| NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov. |
Products Containing the Ingredient
About the ratings
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any.
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