ASCORBYL PALMITATE (VITAMIN C PALMITATE)

Score	Data: Limited
CAS	137-66-6
lipstick (606 products)
lip gloss (227 products)
facial moisturizer/ treatment (200 products)
eye liner (183 products)
eye shadow (173 products)
Show all 2,314 products that contain ASCORBYL PALMITATE (VITAMIN C PALMITATE).
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ASCORBYL PALMITATE (VITAMIN C PALMITATE)

image source: PubChem

Health concerns of ingredient
About the ratings
Cancer	no information
Developmental & reproductive toxicity	no information
Allergies & immunotoxicity	no information
Use restrictions	no information
Contamination concerns: none
Other LOW concerns: Ecotoxicology, Data gaps

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer

Function/use(s): Antioxidant; Fragrance Ingredient; MASKING

About ASCORBYL PALMITATE (VITAMIN C PALMITATE): Ascorbyl Palmitate is a compound composed of of Ascorbic Acid (Vitamin C) and palmitic acid, a naturally occurring fatty acid.

Synonym(s): ASCORBYL PALMITATE, L-ASCORBIC ACID, 6-HEXADECANOATE; ASCORBIC ACID PALMITATE; ASCORBIC PALMITATE; ASCORBYLAPALMITIC ACID; ASCORBYL 6-PALMITATE; PALMITOYL L-ASCORBIC ACID; 6-HEXADECANOATE L-ASCORBIC ACID; 6-O-PALMITOYLASCORBIC ACID; LASCORBIC ACID, 6HEXADECANOATE

Ecotoxicology
type of concern	product conditions	reference
Suspected to be an environmental toxin		Environment Canada Domestic Substance List

Data gaps
type of concern	product conditions	reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in product		Cosmetic Ingredient Review Assessments
196 studies in PubMed science library may include information on the toxicity of this chemical see search results ->		PubMed

Multiple, additive exposure sources
type of concern	product conditions	reference
Designated as safe for general or specific, limited use in food		FDA Everything Added to Food
Designated as safe for general or specific, limited use in food		FDA Food Additive Status

Organ system toxicity (non-reproductive)
type of concern	product conditions	reference
Classified as not expected to be potentially toxic or harmful		Environment Canada Domestic Substance List

Persistence and bioaccumulation

type of concern

product conditions

reference

Not suspected to be persistent

Environment Canada Domestic Substance List

Government, industry, academic studies and classifications
government/industry list/academic study	appears on list as	classification(s)
FDA Food Additive Status	ASCORBYL PALMITATE	• PRES • Status under review • contact CFSAN.
Cosmetic Ingredient Review Assessments	ASCORBYL PALMITATE	QQQ01,QQQ11; M-
FDA Everything Added to Food	ASCORBYL PALMITATE	• ASP
Environment Canada Domestic Substance List	L-ASCORBIC ACID, 6-HEXADECANOATE	,,,,,Y-AquaticTox,,,,
IFRA Fragrance Ingredient List	ASCORBYL 6-PALMITATE	reported as used in fragrance compounds in 2008

Other RTECS® classifications [shown for informational purposes only]
government/industry list/academic study	appears on list as	classification(s)
RTECS^®- FAO Nutrition Meetings Report Series 1974	ASCORBYL PALMITATE (VITAMIN C PALMITATE)	• broad systemic - Broad systemic toxicity (mouse LD50)
RTECS^®- International Journal of Toxicology	ASCORBYL PALMITATE (VITAMIN C PALMITATE)	• metabolic - Weight loss or decreased weight gain (rat TDLo) • kidney or renal system - Interstitial nephritis (rat TDLo) • kidney or renal system - Other changes (rat TDLo)

references
government/industry list/academic study	reference
FDA Food Additive Status	FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
Cosmetic Ingredient Review Assessments	CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
FDA Everything Added to Food	FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
Environment Canada Domestic Substance List	EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
IFRA Fragrance Ingredient List	IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
RTECS^®- FAO Nutrition Meetings Report Series 1974 [shown for informational purposes only]	RTECS^®- FAO Nutrition Meetings Report Series. (Rome, Italy) No.?-57, 1948-77. Discontinued. 53A,146,1974
RTECS^®- International Journal of Toxicology [shown for informational purposes only]	RTECS^®- International Journal of Toxicology. (Taylor & Francis, 47 Runway Rd., Suite g, Levittown, PA 19057) V.16- 1997- 18(Suppl