ALOE BARBADENSIS (ALOE VERA)
About the ratings
EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any.
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Function/use(s): Fragrance Ingredient; MASKING
About ALOE BARBADENSIS (ALOE VERA): Aloe vera is extracted from the succulent leaves of the aloe plant, Aloe barbadensis
Synonym(s): ALOE BARBADENSIS LEAF, ALOE; ALOE EXTRACT (ALOE SPP.) ; ALOE LEAF POWDER; ALOE VERA; ALOE BARBADENSIS; ALOE (LATIN) ; ALOE, POWDERED; AROE (JAPANESE)
Developmental/reproductive toxicity |
| type of concern |
product conditions |
reference |
| One or more animal studies show reproductive effects at moderate doses |
|
CIR (2006) |
Use restrictions |
| type of concern |
product conditions |
reference |
| Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications |
|
Cosmetic Ingredient Review Assessments |
Data gaps |
| type of concern |
product conditions |
reference |
| Missing safety data noted by cosmetic industry review |
|
Cosmetic Ingredient Review Assessments |
| 554 studies in PubMed science library may include information on the toxicity of this chemical
see search results ->
|
|
PubMed |
Multiple, additive exposure sources |
| type of concern |
product conditions |
reference |
| Designated as safe for general or specific, limited use in food |
|
FDA Food Additive Status |
| Designated as safe for general or specific, limited use in food |
|
FDA Everything Added to Food |
Organ system toxicity (non-reproductive) |
| type of concern |
product conditions |
reference |
| Classified as not expected to be potentially toxic or harmful |
|
Environment Canada Domestic Substance List |
Ecotoxicology |
| type of concern |
product conditions |
reference |
| Not suspected to be an environmental toxin |
|
Environment Canada Domestic Substance List |
Government, industry, academic studies and classifications |
| government/industry list/academic study |
appears on list as |
classification(s) |
| FDA Food Additive Status | ALOE | • FL/ADJ • REG • GMP • Used only in conjunction w/flavors - CFR172.510 |
| Cosmetic Ingredient Review Assessments | ALOE BARBADENSIS LEAF | QQQ02,QQQ10,QQQ12,QQQ36; R+, C-, I |
| FDA Everything Added to Food | ALOE, EXTRACT (ALOE SPP.) | • ASP |
| Environment Canada Domestic Substance List | ALOE | ,,,U-Persistent,U-Bioaccumulative,,,,, |
| CIR (2006) | ALOE VERA | 3 month rat study produced significant sperm damage |
Other RTECS® classifications [shown for informational purposes only] |
| government/industry list/academic study |
appears on list as |
classification(s) |
| RTECS®- Mutation Research 1982 | ALOE BARBADENSIS (ALOE VERA) | • mutagenic - Positive mutation assay: DNA repair (Bacillus subtilis )
|
| RTECS®- Mutation Research 1982 | ALOE BARBADENSIS (ALOE VERA) | • mutagenic - Positive mutation assay: DNA repair (Bacillus subtilis )
|
references |
| government/industry list/academic study
| reference
|
| FDA Food Additive Status | FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006. |
| Cosmetic Ingredient Review Assessments | CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC. |
| FDA Everything Added to Food | FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition. |
| Environment Canada Domestic Substance List | EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry. |
| Open scientific literature | CIR (2006). 2006 CIR Compendium. Washington, Cosmetic Ingredient Review. |
| RTECS®- Mutation Research 1982 [shown for informational purposes only] | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 97,81,1982 |
| RTECS®- Mutation Research 1982 [shown for informational purposes only] | RTECS®- Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- -1964 97,81,1982 |
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