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ADIPIC ACID


image source: PubChem
Health Concerns of the Ingredient:
Overall Hazard
 
 
Cancer
 
 
Developmental &
reproductive toxicity
 
 
Allergies & immunotoxicity
 
 

About ADIPIC ACID: Adipic Acid is an organic dicarboxylic acid.

Function(s): Fragrance Ingredient; pH Adjuster; BUFFERING; MASKING

Synonym(s): 1,4-BUTANEDICARBOXYLIC ACID; HEXANEDIOIC ACID; 1,4-BUTANEDICARBOXYLIC ACID; 1,6-HEXANEDIOIC ACID; ACIFLOCTIN; ACINETTEN; ADILACTETTEN; ADIPIC ACID (ACGIH) ; ADIPINIC ACID; HEXANEDIOIC ACID; KYSELINA ADIPOVA (CZECH)

Irritation (skin, eyes, or lungs)

Concern Reference
Classified as irritantEuropean Union - Classification & Labelling

Use restrictions

Concern Reference
Determined safe for use in cosmetics, subject to concentration or use limitations - Distinction between safe conc in leave-on and rinse-off (only for products that are intended to be left on the skin)Cosmetic Ingredient Review Assessments

Ecotoxicology

Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Cancer

Concern Reference
Not likely to be carcinogenic in humansEPA Water Disinfection By-Products Carcinogenicity

Data gaps

Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
741 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Persistence and bioaccumulation

Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Multiple, additive exposure sources

Concern Reference
Designated as safe for general or specific, limited use in foodFDA Food Additive Status
Designated as safe for general or specific, limited use in foodFDA Everything Added to Food

Data Sources

CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
EPA (U.S. Environmental Protection Agency). 2006. EPA Water Disinfection By-Products with Carcinogenicity Estimates. Last updated: 10 April 2006.
FDA (U.S. Food and Drug Administration) 2006. Food Additive Status List. Downloaded from http://www.cfsan.fda.gov/%7Edms/opa-appa.html, Oct 16, 2006.
FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer