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ACETYL TRIBUTYL CITRATE


image source: PubChem
Health Concerns of the Ingredient:
Overall Hazard
 
 
Cancer
 
 
Developmental &
reproductive toxicity
 
 
Allergies & immunotoxicity
 
 
Use restrictions
 
 
Other HIGH concerns: Multiple, additive exposure sources; Other LOW concerns: Data gaps

About ACETYL TRIBUTYL CITRATE: Acetyl Tributyl Citrate is an aliphatic ester.

Function(s): Fragrance Ingredient; Plasticizer; FILM FORMING; MASKING; PERFUMING; PLASTICISER

Synoym(s): 1,2,3-PROPANETRICARBOXYLIC ACID, 2- (ACETYLOXY) -, TRIBUTYL ESTER; 1,2,3PROPANETRICARBOXYLIC ACID, 2 (ACETYLOXY) , TRIBUTYL ESTER; 2- (ACETYLOXY) - TRIBUTYL ESTER 1,2,3-PROPANETRICARBOXYLIC ACID; 2- (ACETYLOXY) -1,2,3-PROPANETRICARBOXYLIC ACID, TRIBUTYL ESTER; ACETATE CITRIC ACID, TRIBUTYL ESTER; ACETYLCITRIC ACID TRIBUTYL ESTER; ATBC; ATEC; CITRIC ACID, TRIBUTYL ESTER, ACETATE; TRIBUTYL ACETYLCITRATE; TRIBUTYL ESTER 1,2,3-PROPANETRICARBOXYLIC ACID, 2- (ACETYLOXY) -

Multiple, additive exposure sources

Concern Reference
Used in food or as an additive with limited or no toxicity information availableFDA Everything Added to Food

Ecotoxicology

Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
204 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Organ system toxicity (non-reproductive)

Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Persistence and bioaccumulation

Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Data Sources

CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
FDA (U.S. Food and Drug Administration). 2008. EAFUS [Everything Added to Food]: A Food Additive Database. FDA Office of Food Safety and Applied Nutrition.
IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer