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ZINC


image source: PubChem
Health Concerns of the Ingredient:
Overall Hazard
 
 
Cancer
 
 
 
 
Use restrictions
 
 
Other HIGH concerns: Ecotoxicology, Persistence and bioaccumulation; Other LOW concerns: Enhanced skin absorption, Data gaps, Organ system toxicity (non-reproductive), Occupational hazards

About ZINC: Any compound that contains zinc in its chemical structure.

Synoym(s): ZINC, DISSOLVED; ZINC, TOTAL; ZN; BLUE POWDER; GRANULAR ZINC; LS 2; LS 6; MERRILLITE; RHEINZINK; ZINC DUST; ZINC POWDER

Allergies/immunotoxicity

Concern Reference
Limited evidence of immune system toxicity or allergiesCalifornia EPA, Office of Environmental Health Hazard Assessment

Ecotoxicology

Concern Reference
Wildlife and environmental toxicityEPA Clean Water Act - Priority Pollutants
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Developmental/reproductive toxicity

Concern Reference
Limited evidence of developmental toxicityUS EPA
Limited evidence of reproductive toxicityUS EPA

Persistence and bioaccumulation

Concern Reference
Persistent, bioaccumulative in wildlifeCanada PBTs - Accelerated Reduction/Elimination of Toxics (ARET)
Found to be persistent and bioaccumulative in wildlifeBorgå K, Campbell L, Gabrielsen GW, Norstrom RJ, Muir DC, Fisk AT
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

Concern Reference
Limited evidence of cardiovascular or blood toxicityAgency for Toxic Substances and Disease Registry
Limited evidence of respiratory toxicityNemery, B
Limited evidence of respiratory toxicity (only for products that may be aerosolized (airborne))California EPA, Office of Environmental Health Hazard Assessment
Limited evidence of toxicityCalifornia EPA, Office of Environmental Health Hazard Assessment
One or more animal studies show classified as toxic effects at moderate doses (low dose studies may be unavailable for this ingredient)EPA Toxic Release Inventory PBTs
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Occupational hazards

Concern Reference
Allowed workplace exposures restricted to very low dosesEuropean Union - Classification & Labelling
Allowed workplace exposures restricted to very low doses (only for products that may be aerosolized (airborne))European Union - Classification & Labelling

Miscellaneous

Concern Reference
Occupational hazards related to handlingEuropean Union - Classification & Labelling

Data gaps

Concern Reference
Insufficient data to determine safetyEPA Integrated Risk Information System (IRIS)
119,593 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Enhanced skin absorption

Concern Reference
Suspected nano-scale ingredients with potential to absorb into the skinNanomaterial Database

Cancer

Concern Reference
Cancer - not classifiable/not likely to be human carcinogenEPA Integrated Risk Information System (IRIS)

Data Sources

AOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
Agency for Toxic Substances and Disease Registry. Minimal risk Levels for Hazardous Substances. January 2004. http://www.atsdr.cdc.gov/mrls.html
Borgå K, Campbell L, Gabrielsen GW, Norstrom RJ, Muir DC, Fisk AT. 2006. Regional and species specific bioaccumulation of major and trace elements in Arctic seabirds. Environ Toxicol Chem. 2006 Nov;25(11):2927-36.
CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document
California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document
California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document 'Determination of Noncancer Chronic Reference Exposure Levels'. Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html.
EC (Environment Canada). 1994. Accelerated Reduction/Elimination of Toxics (ARET). ARET substance list of persistent, bioaccumulative and toxic chemicals.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
EPA (U.S. Environmental Protection Agency). 1999. Toxics Release Inventory Program. PBT Chemical Rule.
EPA (U.S. Environmental Protection Agency). 2008. Integrated Risk Information System (IRIS). Evidence for human carcinogenicity based on 1986-2005 guidelines.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.
NanoWerk. 2007. Nanomaterial Database. Available online: http://www.nanowerk.com/phpscripts/n_dbsearch.php
Nemery, B. Metal Toxicity and the Respiratory Tract. European Respiratory Journal. 3(2): 202-219. 1990.(Table 1: Summary of pulmonary toxicity of metals).; California EPA, Office of Environmental Health Hazard Assessment. Air Toxics Hot Spots Program Risk Assessment Guidelines, Part III: Technical Support Document 'Determination of Noncancer Chronic Reference Exposure Levels'. Includes all Chronic Reference Exposure Levels (CRELs) adopted by OEHHA as of August 2003 (http://www.oehha.ca.gov/air/chronic_rels/AllChrels.html, plus draft CRELS proposed through March 2004 (http://www.oehha.ca.gov/air/chronic_rels/index.html.
US EPA. Roadmaps to Sources of Information on Chemicals Listed in the Emergency Planning Community and Community Right-to-Know Act (Also Known as SARA Title 3), Section 313 Toxic Release Inventory (for Microcomputers). (Report Number EPADFDK92040). 1991. Data file distributed in 2 diskettes by Office of Pollution, Prevention, and Toxics, Environmental Protection Agency, Washington, DC. NOTE: Datasource no longer being maintained by EPA; not currently available online.
US EPA. Roadmaps to Sources of Information on Chemicals Listed in the Emergency Planning Community and Community Right-to-Know Act (Also Known as SARA Title 3), Section 313 Toxic Release Inventory (for Microcomputers). (Report Number EPADFDK92040). 1991. Data file distributed in 2 diskettes by Office of Pollution, Prevention, and Toxics, Environmental Protection Agency, Washington, DC. NOTE: Datasource no longer being maintained by EPA; not currently available online.

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer