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Score:
Data available:
 
Fair

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HEXYLENE GLYCOL


image source: PubChem
Health Concerns of the Ingredient:
Overall Hazard
 
 
Cancer
 
 
Developmental &
reproductive toxicity
 
 
 
Use restrictions
 
 
Other HIGH concerns: Irritation (skin, eyes, or lungs); Other LOW concerns: Data gaps

About HEXYLENE GLYCOL: Hexylene glycol is a small molecular weight surfactant.

Function(s): Fragrance Ingredient; Solvent; Viscosity Decreasing Agent; EMULSIFYING; PERFUMING; SKIN CONDITIONING; SURFACTANT

Synoym(s): 1,1,3-TRIMETHYLTRIMETHYLENEDIOL; 2,4-DIHYDROXY-2-METHYLPENTANE; 2,4-PENTANEDIOL, 2-METHYL-; 2,4PENTANEDIOL, 2METHYL; 2-METHYL- 2,4-PENTANEDIOL; 2-METHYL-2,4-PENTANDIOL; 2-METHYL-2,4-PENTANEDIOL; 2-METHYLPENTANE-2,4-DIOL; HEXYLENE GYCOL; MPD; 2,4-DIHYDROXY-2-METHYLPENTANE

Allergies/immunotoxicity

Concern Reference
Limited evidence of immune system toxicity or allergiesNational Library of Medicine HazMap

Irritation (skin, eyes, or lungs)

Concern Reference
Classified as irritantEuropean Union - Classification & Labelling

Data gaps

Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
2,282 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Ecotoxicology

Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Neurotoxicity

Concern Reference
nervous system - weight of evidence unknown/unassessed/unreview: published lit review or major tox studyNational Library of Medicine HazMap

Persistence and bioaccumulation

Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List
Classified as a low human health priorityEnvironment Canada Domestic Substance List

Data Sources

AOEC (Association of Occupational and Environmental Clinics). 2009. AEOC exposures codes and asthmagen designation.
CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
CPS&Q (Consumer Products Safety & Quality) formely known as ECB (European Chemicals Bureau). 2008. Classification and Labelling: Chemicals: Annex VI of Directive 67/548/EEC through the 31st ATP.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer