ewg.org | About SkinDeep®/Methodology | Terms & Conditions | Build Your Own Report | FAQ
 
Score:
Data available:
 
Limited

Get The Guide!

Want a free Cosmetics Guide? Donate $5 to EWG today!

Sign Up!

DMDM HYDANTOIN (FORMALDEHYDE RELEASER)


image source: PubChem
Health Concerns of the Ingredient:
Overall Hazard
 
 
 
 
Developmental &
reproductive toxicity
 
 
 

About DMDM HYDANTOIN (FORMALDEHYDE RELEASER): DMDM hydantoin is an antimicrobial formaldehyde releaser preservative. People exposed to such formaldehyde-releasing ingredients may develop a formaldehyde allergy or an allergy to the ingredient itse ... read more

Function(s): Preservative

Synoym(s): DMDM HYDANTOIN, 1,3-BIS (HYDROXYMETHYL) -5,5-DIMETHYL- 2,4-IMIDAZOLIDINEDIONE; 1,3-BIS (HYDROXYMETHYL) -5,5-DIMETHYLIMIDAZOLIDINE-2,4-DIONE; 1,3-BIS (HYDROXYMETHYL) -5,5-DIMETHYLIMIDAZOLIDINE-2,4-DIONE (+) ; 1,3-DIHYDROXYMETHYL-5,5 DIMETHYLHYDANTOIN; 1,3-DIMETHYLOL-5,5-DIMETHYL HYDANTOIN; 2,4-IMIDAZOLIDINEDIONE, 1,3-BIS (HYDROXYMETHYL) -5,5-DIMETHYL-; 2,4IMIDAZOLIDINEDIONE, 1,3BIS (HYDROXYMETHYL) 5,5DIMETHYL; 1,3-BIS (HYDROXYMETHYL) -5,5-DIMETHYLHYDANTOIN; 2,4-IMIDAZOLIDINEDIONE, 1,3-BIS (HYDROXYMETHYL) -5,5-DIMETHYL- (9CI) ; DANTOIN DMDMH 55; DIMETHYLOL-5,5-DIMETHYLHYDANTOIN

Allergies/immunotoxicity

Concern Reference
Known human immune toxicant or allergen
Human skin toxicant or allergen - strong evidenceCosmetic Ingredient Review Assessments
Limited evidence of immune system toxicity or allergiesNational Library of Medicine HazMap

Use restrictions

Concern Reference
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - restricted for use in some types of cosmetics (concentration limit)Japan's Standards for Cosmetics
Restricted in cosmetics (recommendations or requirements) - use, concentration, or manufacturing restrictions - Japan - prohibited for use in some types of cosmeticsJapan's Standards for Cosmetics

Cancer

Concern Reference
Cancer - limited evidenceIARC (International Agency for Research on Cancer)

Irritation (skin, eyes, or lungs)

Concern Reference
Human irritant - strong evidence (only for products for use around the eyes, on the skin, or may be aerosolized (airborne))Cosmetic Ingredient Review Assessments

Ecotoxicology

Concern Reference
Not suspected to be an environmental toxinEnvironment Canada Domestic Substance List

Data gaps

Concern Reference
Risk assessment method deficiencies and data gaps - Maximum reported "as used" concentration is basis of safety assessment by industry safety panel (Cosmetic Ingredient Review, CIR) - implicit safe concentration limit in productCosmetic Ingredient Review Assessments
24 studies in PubMed science library may include information on the toxicity of this chemical see search results ->NLM PubMed

Persistence and bioaccumulation

Concern Reference
Not suspected to be persistentEnvironment Canada Domestic Substance List
Not suspected to be bioaccumulativeEnvironment Canada Domestic Substance List

Organ system toxicity (non-reproductive)

Concern Reference
Classified as not expected to be potentially toxic or harmfulEnvironment Canada Domestic Substance List

Chemical release concerns

Chemical Score
FORMALDEHYDE
Data: Fair

Data Sources

CIR (Cosmetic Ingredient Review). 2006. CIR Compendium, containing abstracts, discussions, and conclusions of CIR cosmetic ingredient safety assessments. Washington DC.
EC (Environment Canada). 2008. Domestic Substances List Categorization. Canadian Environmental Protection Act (CEPA) Environmental Registry.
European Commission. 2013. Cosing, the European Commission database with information on cosmetic substances and ingredients. Accessed on March 1, 2013 at http://ec.europa.eu/consumers/cosmetics/cosing/ .
Formaldehyde - Global Harmonized System (GHS) Hazard Codes
IARC (International Agency for Research on Cancer). 2008. Overall Evaluations of Carcinogenicity to Humans, as evaluated in IARC Monographs Volumes 1-99.
IFRA (International Fragrance Assocication). 2010. IFRA Fragrance Ingredient List based on 2008 Use Survey. Accessed online 01/04/2010: http://www.ifraorg.org/Home/News/Latest-News/page.aspx/66?xf_itemId=43&xf_selectionDatapartId=25
Japan Ministry of Health, Labour and Welfare. 2006. Standards for Cosmetics. Evaluation and Licensing Division. Pharmaceutical and Food Safety Bureau.
NLM (National Library of Medicine). 2006. HazMap — Occupational Exposure to Hazardous Agents.
NLM (National Library of Medicine). 2012. PubMed online scientific bibliography data. http://www.pubmed.gov.

About the ratings

EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. Learn more | Legal Disclaimer