chemical Class

Bisphenol A & BADGE


Chemicals in the class:

BADGE-4OH, Bisphenol A





Bisphenol A & BADGE

Top health concerns for Bisphenol A & BADGE (References)

health concern or target organ weight of evidence
Endocrine systemstrong
Skinlimited

Other health concerns for Bisphenol A & BADGE (References)

health concern or target organ weight of evidence
Immune system (including sensitization and allergies)unknown
Cancerlimited
Sense organslimited
Reproduction and fertilityunknown
Persistent, accumulates in wildlife and/or peopleprobable
Birth defects and developmental delayslimited
Kidney and renal systemlimited

Other relevant risk considerations for Bisphenol A & BADGE (References)

Wildlife and environmental toxicity.


Toxicity Classifications (References)

classification governing entity/references
Benign prostatic hypertrophy - LimitedCHE Toxicant and Disease Database
Congenital malformations - general - LimitedCHE Toxicant and Disease Database
EPA: probable endocrine disruptorIllinois EPA Chemicals Associated with Endocrine System
Endocrine disruptorHanaoka, T., N. Kawamura, et al. (2002). Urinary bisphenol A and plasma hormone concentrations in male workers exposed to bisphenol A diglycidyl ether and mixed organic solvents. Occup Environ Med 59(9): 625-8.
Endocrine toxicity hazards: suspectedBKH, GUIL, IL-EPA, JNIHS, KEIT, RTECS, WWF
Fetotoxicity (Miscarriage/spontaneous abortion, stillbirth) - GoodCHE Toxicant and Disease Database
Genito-urinary malformations (includes male and female) - LimitedCHE Toxicant and Disease Database
IARC 3: mixed or limited evidence on human cancer potential (International Agency for Research on Carcinogens)Inter'l Agency for Research on Cancer (IARC) Carcinogens
Immune system toxicity - weight of evidence unknown/unassessedSugita-Konishi, Y., S. Shimura, et al. (2003). Effect of Bisphenol A on non-specific immunodefenses against non-pathogenic Escherichia coli. Toxicol Lett 136(3): 217-27.
Immunotoxicity hazards: suspectedEEC, HAZMAP, SNCI
Irritant; Irritating to eyes and skin; May cause sensitization by skin contactEuropean Union - Classification & Labelling
Limited evidence in humans: reproductive system toxicity; Condition: abnormal sperm (morphology, motility, and sperm count); Organs/tissues affected: testesCHE Toxicant and Disease Database
Limited evidence of reproductive toxicity (European Union classification); Possible risk of impaired fertility; Irritant; Irritating to respiratory system; May cause sensitization by skin contactEuropean Union - Classification & Labelling
May cause sensitization by skin contact, with allergic reaction in skin or lungsNational Library of Medicine HazMap
Menstrual disorders (abnormal bleeding, short cycles, long cycles, irregular cycles, painful periods) - LimitedCHE Toxicant and Disease Database
Persistent, bioaccumulative toxicant - Limited or emerging evidence in open scientific literatureEmerging PBTs from peer-reviewed literature
Persistent, bioaccumulative toxicant - Oslo-Paris (OSPAR) Convention for the Protection of the Marine Environment of the North-East Atlantic, chemical of concernOSPAR (2002). OSPAR List of Substances of Possible Concern. Secondary OSPAR List of Substances of Possible Concern. Secondary OSPAR. Place Published, OSPAR Convention for the Protection of the Marine Environement of North-East Atlanic.
Prostate cancer - LimitedCHE Toxicant and Disease Database
Reduced Fertility - Male (infertility and subfertility) - LimitedCHE Toxicant and Disease Database
Reproductive toxicity hazards: suspectedJANK, NTP-R
Skin or sense organ toxicity hazards: suspectedEEC, HAZMAP, HAZMAP, KLAA
Toxic, U.S. Environmental Protection Agency Toxics Release Inventory programsEPA Toxic Release Inventory (1999)