chemical information
CAS RN:

307-55-1

Chemical Class:

Perfluorochemical (PFC)

Chemical SubClass

Perfluorinated carboxylic acid

Manufacturing/Use Status

there are no restrictions on the production/use in the U.S.

Found in these people:

Adult #108, Participant #8, Kelsey Wirth, Nina Damato, Nora Pouillon

Found in these locations:

Washington, DC; Cambridge, MA

Exposure routes:

Stain- and grease-proof coatings on food packaging, couches, carpets.


Summary

Perfluorododecanoic acid (PFDoA) is a breakdown product of stain- and grease-proof coatings on food packaging, couches, and carpets, including Stainmaster. The chemical is part of a family of perfluoroalkyl carboxylates, all with structures similar to the well-known chemical contaminant PFOA, but with carbon chain lengths ranging from 4 to 15 carbons. PFDoA is the 12 carbon version of PFOA.

All of these perfluoroalkyl carboxylates are highly persistent. But those with carbon chain lengths of at least 8 carbons are of particular concern because they are known to be bioaccumulative, globally distributed pollutants. These chemicals have been found in human and wildlife blood and tissues from around the globe, even in remote locations such as the arctic (3M 2000; Bossi 2005; Guruge 2005; Smithwick 2005; Van de Vijver 2005; Lange 2006).

While there has been very little research done on the toxicity of PFDoA itself, PFOA has been studied extensively. Animal studies have linked PFOA exposure to low birth weight, decreased growth, decreased pituitary size, increased number of dead or cannibalized pups, decreased breast-feeding, decreased liver size, delayed puberty, altered reproductive cycles and hormone levels, decreased kidney size, immune system problems, cancer, and death (EPA 2002; York 2002). In January of 2006, the Environmental Protection Agency's (EPA) Science Advisory Board recommended that PFOA be classified as a likely human carcinogen.

In January of 2006, the EPA asked eight manufacturers that use PFOA to reduce production 95% by 2010, and to stop using it altogether by 2015. But because PFOA never breaks down, this means that every PFOA molecule on the planet is here to stay; opportunities for humans (and other animals) to be exposed continuously to PFOA will continue even after production ceases. Furthermore, similar action has not been taken on chemicals that break down into PFOA or its related perfluoroalkyl carboxylates, making EPA's action even less effective for actually making meaningful reductions in exposures to these compounds.


PFDoA (Perfluorododecanoic acid)

Breakdown product of stain- and grease-proof coatings on food packaging, couches, carpets, including Stainmaster. Highly persistent and bioaccumulative.

PFDoA (Perfluorododecanoic acid) has been found in 5 of the 88 people tested in EWG/Commonweal studies. It has also been found in 1 of the 2,368 people tested in CDC biomonitoring studies.



Results for PFDoA (Perfluorododecanoic acid)

PFDoA (Perfluorododecanoic acid) was measured in different units for some of the studies. Overall it was found in 5 of 88 people tested in EWG/Commonweal studies. The bars below are grouped by units:

in whole blood (wet weight)

Showing results from EWG/Commonweal Study #4, industrial chemicals and pesticides in cord blood, Pollution in Minority Newborns, EWG Study #3, industrial chemicals and pesticides in adults

EWG/Commonweal results

  • found in 0 of 23 people in the group

found in 0 of 23 people

in blood serum (wet weight)

Showing results from EWG Study #5, Teflon and mercury in blood in adults and teens

EWG/Commonweal results

  • geometric mean: 0.0802 ng/g (wet weight) in blood serum
  • found in 4 of 8 people in the group
0 ng/g (wet weight) in blood serum 0.168


PFDoA (Perfluorododecanoic acid) results

in blood serum (wet weight)

Showing results from EWG/Commonweal Study #7, consumer product chemicals in adults and teens, EWG Study #6, consumer product chemicals in mothers and daughters, Pets Project, Dateline NBC Families, Dateline NBC Families, Other Body Burden Studies, Adult Minority Leader Report, EWG Study #8, chemicals in mother and 2 children

EWG/Commonweal results

  • found in 1 of 57 people in the group

CDC biomonitoring results

  • geometric mean: 0.672 ng/mL (wet weight) in blood serum
  • found in 1 of 2368 people in the group
0 ng/mL (wet weight) in blood serum 1


PFDoA (Perfluorododecanoic acid) results