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The Joint FAO/WHO Expert Committee on Food Additives reports that this substance causes damage to breastfeeding animals at high doses.
Only in: Food Scores®
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high
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Joint FAO/WHO Expert Committee on Food Additives (JECFA). 1987. 30th Report of the Joint FAO/WHO Expert Committee on Food Additives. World Health Organization Technical Report Series 751.
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|
The Joint FAO/WHO Expert Committee on Food Additives reports that this substance causes blood effects in animals at high doses.
Only in: Food Scores®
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high
|
Joint FAO/WHO Expert Committee on Food Additives (JECFA). 1987. 30th Report of the Joint FAO/WHO Expert Committee on Food Additives. World Health Organization Technical Report Series 751.
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|
The Joint FAO/WHO Expert Committee on Food Additives reports that this substance causes damage to breastfeeding animals at high doses.
Only in: Food Scores®
|
high
|
Joint FAO/WHO Expert Committee on Food Additives (JECFA). 1987. 30th Report of the Joint FAO/WHO Expert Committee on Food Additives. World Health Organization Technical Report Series 751.
|
|
The Joint FAO/WHO Expert Committee on Food Additives reports that this substance causes blood effects in animals at high doses.
Only in: Food Scores®
|
moderate
|
Joint FAO/WHO Expert Committee on Food Additives (JECFA). 1987. 30th Report of the Joint FAO/WHO Expert Committee on Food Additives. World Health Organization Technical Report Series 751.
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|
A Cosmetic Ingredient Review panel reports this substance causes blood effects in animals at high doses.
Only in: Food Scores®
|
some
|
Monice Zondlo Fiume. 2002. Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophe. International journal of toxicology 21 Suppl 3, 51-116.
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A Cosmetic Ingredient Review panel reports this substance causes blood effects in animals at high doses.
Only in: Food Scores®
|
some
|
Monice Zondlo Fiume. 2002. Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophe. International journal of toxicology 21 Suppl 3, 51-116.
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|
The CIR panel reports equivocal evidence that tocopherol may act as a tumor promoter.
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some
|
Cosmetic Ingredient Review (CIR): CIR Assessments
|
|
May cause an allergic skin reaction
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
Suspected of causing genetic defects
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
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|
Suspected of causing cancer
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
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|
Very toxic to aquatic life
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
eye damage
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
|
Harmful if swallowed
Only in: Household Cleaners
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some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
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|
The CIR panel reports that tocopherol was a dermal sensitizer in an animal study and contact allergy has been reported in human tests and case studies, although occurrence is rare.
|
some
|
Cosmetic Ingredient Review (CIR): CIR Assessments
|
|
confirmed animal carcinogen with unknown relevance to humans
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
|
May cause an allergic skin reaction
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
Causes serious eye damage
Only in: Drain Opener/Clog Remover; Oven Cleaner; Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
NTP Toxcast scored 1.5-2.5
|
some
|
National Toxicology Program (NTP): EWG Toxcast Analysis
|
|
Not classifiable as to its carcinogenicity to humans
|
low
|
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
|
|
eye irritation
|
low
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
|
Tocopherol functions as an antioxidant in personal care products.
|
low
|
Cosmetic Ingredient Review (CIR): CIR Assessments
|
|
Tocopherol was not genotoxic in in vitro tests with mammalian cells.
|
low
|
Cosmetic Ingredient Review (CIR): CIR Assessments
|
|
A Cosmetic Ingredient Review panel reports this substance is not a sensitizer
|
low
|
Monice Zondlo Fiume. 2002. Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophe. International journal of toxicology 21 Suppl 3, 51-116.
|
|
A Cosmetic Ingredient Review panel reports this substance is not a sensitizer
|
low
|
Monice Zondlo Fiume. 2002. Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophe. International journal of toxicology 21 Suppl 3, 51-116.
|
|
This substance is Generally Recognized as Safe (GRAS) as a food additive by the US Food and Drug Administration
Only in: Household Cleaners
|
low
|
U.S. Food and Drug Administration (FDA): FDA - Priority based Assessment of Food Additive (PAFA)
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