Health issue
Level of Concern
Source
fatal if inhaled
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
toxic if inhaled
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
harmful in inhaled
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Causes serious eye damage
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
Causes skin irritation
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
causes serious eye irritation
Only in: Household Cleaners
some
European Chemicals Agency (ECHA): GHS Data from ECHA Website
The Cosmetic Ingredient Review panel concludes this substance is safe for use when formulated to be non-irritating.
some
Cosmetic Ingredient Review (CIR): CIR Assessments
A Cosmetic Ingredient Review Expert Panel found that acyl sarcosines and sarcosinates are not skin irritants at concentrations relevant to cleaners.
low
R. S. Lanigan. 2001. Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl Sarcosinate, Sodium Lauroyl Sarcosinate, Sodium Myristoyl Sarcosinate, Ammonium Cocoyl Sarcosinate, and. International journal of toxicology 20 Suppl 1, 1-14.
European Union Ecolabel program data shows this substance has moderate acute toxicity to aquatic life
low
EU Ecolabel: Detergents Ingredients Database
European Union Ecolabel program data shows this substance has moderate acute toxicity to aquatic life
low
EU Ecolabel: Detergents Ingredients Database
A Cosmetic Ingredient Review Expert Panel found that acyl sarcosines and sarcosinates are not skin sensitizers.
low
R. S. Lanigan. 2001. Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl Sarcosinate, Sodium Lauroyl Sarcosinate, Sodium Myristoyl Sarcosinate, Ammonium Cocoyl Sarcosinate, and. International journal of toxicology 20 Suppl 1, 1-14.
A Cosmetic Ingredient Review Expert Panel reported the lowest acute LD50 for acyl sarcosinates determined by industry studies was 4,200 mg/kg body weight.
low
R. S. Lanigan. 2001. Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl Sarcosinate, Sodium Lauroyl Sarcosinate, Sodium Myristoyl Sarcosinate, Ammonium Cocoyl Sarcosinate, and. International journal of toxicology 20 Suppl 1, 1-14.
A Cosmetic Ingredient Review Expert Panel found limited evidence to indicate that acyl sarcosines and sarcosinates are not toxic to reproduction.
low
R. S. Lanigan. 2001. Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl Sarcosinate, Sodium Lauroyl Sarcosinate, Sodium Myristoyl Sarcosinate, Ammonium Cocoyl Sarcosinate, and. International journal of toxicology 20 Suppl 1, 1-14.
This chemical has been verified to be of low concern in cleaning products based on experimental and modeled data as assessed by the EPA.
low
Environmental Protection Agency (EPA): Safer Chemical Ingredients List (2018-02-28)
The European Union Ecolabel program reports this substance is readily biodegradable.
low
EU Ecolabel: Detergents Ingredients Database
The European Union Ecolabel program reports this substance is anaerobically degradable.
low
EU Ecolabel: Detergents Ingredients Database
The European Union Ecolabel program reports this substance is readily biodegradable.
low
EU Ecolabel: Detergents Ingredients Database
The European Union Ecolabel program reports this substance is anaerobically degradable.
low
EU Ecolabel: Detergents Ingredients Database
Health issue
Level of Concern
Source
Impurity: NITROSAMINES
Known to cause cancer
some
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
Impurity: NITROSAMINES
Probably carcinogenic to humans
some
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
Impurity: NITROSAMINES
Probably carcinogenic to humans
some
Environmental Protection Agency (EPA): EPA Integrated Risk Information System (IRIS) - Cancer
Impurity: NITROSAMINES
Reasonably Anticipated To Be Human Carcinogen
some
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
Impurity: NITROSAMINES
NTP Toxcast scored 1.5-2.5
some
National Toxicology Program (NTP): EWG Toxcast Analysis