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The Agency for Toxic Substances and Disease Registry reports the metabolite of this substance causes effects on the blood at very high doses in laboratory animals.
Only in: Food Scores®
|
high
|
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 1997. TOXICOLOGICAL PROFILE FOR PROPYLENE GLYCOL.
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|
The Agency for Toxic Substances and Disease Registry reports this substance causes effects on the blood at very high doses in laboratory animals.
Only in: Food Scores®
|
moderate
|
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 1997. TOXICOLOGICAL PROFILE FOR PROPYLENE GLYCOL.
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|
The Joint FAO/WHO Expert Committee on Food Additives reports this substances causes blood effects in laboratory animals at high doses.
Only in: Food Scores®
|
moderate
|
Joint FAO/WHO Expert Committee on Food Additives (JECFA). 1974. Toxicological evaluation of some food additives including anticaking agents, antimicrobials, antioxidants, emulsifiers, and thickening agents. WHO Food Additives Series, No. 5, 1974, nos 257-353 on INCHEM.
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|
The Agency for Toxic Substances and Disease Registry found cases of sensitivity recorded in the Propylene Glycol literature and concluded that it might be a sensitizer.
|
some
|
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 1997. Toxicological Profile For Propylene Glycol.
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|
The Agency for Toxic Substances and Disease Registry concluded that Propylene Glycol has marginal irritant properties.
|
some
|
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 1997. Toxicological Profile For Propylene Glycol.
|
|
NTP Toxcast scored 1.5-2.5
|
some
|
National Toxicology Program (NTP): EWG Toxcast Analysis
|
|
The OECD concluded that Propylene Glycol is not a skin irritant.
|
low
|
Organisation for Economic Co-Operation and Development. 2001. Propylene glycol CAS No. 57-55-6. SIDS Initial Assessment Report for 11th SIAM.
|
|
The OECD concluded that Propylene Glycol does not cause sensitization by skin contact.
|
low
|
Organisation for Economic Co-Operation and Development. 2001. Propylene glycol CAS No. 57-55-6. SIDS Initial Assessment Report for 11th SIAM.
|
|
The OECD reported that Propylene Glycol has ecotoxicity.
|
low
|
Organisation for Economic Co-Operation and Development. 2001. Propylene glycol CAS No. 57-55-6. SIDS Initial Assessment Report for 11th SIAM.
|
|
European Union Ecolabel program data shows this substance has moderate acute toxicity to aquatic life
Only in: Household Cleaners
|
low
|
EU Ecolabel: Detergents Ingredients Database
|
|
This substance is Generally Recognized as Safe (GRAS) as a food additive by the US Food and Drug Administration
Only in: Household Cleaners
|
low
|
U.S. Food and Drug Administration (FDA): FDA - Priority based Assessment of Food Additive (PAFA)
|
|
The European Union Ecolabel program reports this substance is readily biodegradable.
|
low
|
EU Ecolabel: Detergents Ingredients Database
|
|
The European Union Ecolabel program reports this substance is anaerobically degradable.
|
low
|
EU Ecolabel: Detergents Ingredients Database
|
|
The OECD reported that Propylene Glycol has low oral acute toxicity.
|
low
|
Organisation for Economic Co-Operation and Development. 2001. Propylene glycol CAS No. 57-55-6. SIDS Initial Assessment Report for 11th SIAM.
|
|
The OECD reported that Propylene Glycol has low dermal acute toxicity.
|
low
|
Organisation for Economic Co-Operation and Development. 2001. Propylene glycol CAS No. 57-55-6. SIDS Initial Assessment Report for 11th SIAM.
|
|
The OECD concluded that Propylene Glycol is not genotoxic.
|
low
|
Organisation for Economic Co-Operation and Development. 2001. Propylene glycol CAS No. 57-55-6. SIDS Initial Assessment Report for 11th SIAM.
|
|
The OECD concluded that there is no evidence to suggest that Propylene Glycol has any carcinogenic potential.
|
low
|
Organisation for Economic Co-Operation and Development. 2001. Propylene glycol CAS No. 57-55-6. SIDS Initial Assessment Report for 11th SIAM.
|
|
The OECD concluded that Propylene Glycol is not a reproductive/developmental toxicant.
|
low
|
Organisation for Economic Co-Operation and Development. 2001. Propylene glycol CAS No. 57-55-6. SIDS Initial Assessment Report for 11th SIAM.
|
|
The Agency for Toxic Substances and Disease Registry reported oral LD50 values for Propylene Glycol present in the scientific literature.
|
low
|
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 1997. Toxicological Profile For Propylene Glycol.
|
|
The Agency for Toxic Substances and Disease Registry concluded that there is no evidence that Propylene Glycol is carcinogenic in humans or animals
|
low
|
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 1997. Toxicological Profile For Propylene Glycol.
|
|
The Agency for Toxic Substances and Disease Registry found no evidence of in vitro genotoxicity.
|
low
|
U.S. Department of Health and Human Services - Agency for Toxic Substances and Disease Registry. 1997. Toxicological Profile For Propylene Glycol.
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