|
A U.S. Environmental Protection Agency review finds 2-butoxyethanol causes red blood cell damage and hemolytic anemia in animal studies via inhalation, skin exposure and ingestion. Humans may be less sensitive.
|
high
|
U.S. Environmental Protection Agency. 2010. Toxicological Review of Ethylene Glycol Monobutyl Ether (EGBE) (CAS No. 111-76-2) In Support of Summary Information on the Integrated Risk Information System (IRIS). EPA/635/R-08/006F.
|
|
A U.S. Environmental Protection Agency review finds inhalation of 2-butoxyethanol causes liver damage in lab animals.
|
high
|
U.S. Environmental Protection Agency. 2010. Toxicological Review of Ethylene Glycol Monobutyl Ether (EGBE) (CAS No. 111-76-2) In Support of Summary Information on the Integrated Risk Information System (IRIS). EPA/635/R-08/006F.
|
|
A U.S. Environmental Protection Agency review finds ingestion of 2-butoxyethanol causes liver damage in lab animals.
|
high
|
U.S. Environmental Protection Agency. 2010. Toxicological Review of Ethylene Glycol Monobutyl Ether (EGBE) (CAS No. 111-76-2) In Support of Summary Information on the Integrated Risk Information System (IRIS). EPA/635/R-08/006F.
|
|
A U.S. Environmental Protection Agency review finds inhalation of 2-butoxyethanol causes forestomach ulcers in lab animals.
|
high
|
U.S. Environmental Protection Agency. 2010. Toxicological Review of Ethylene Glycol Monobutyl Ether (EGBE) (CAS No. 111-76-2) In Support of Summary Information on the Integrated Risk Information System (IRIS). EPA/635/R-08/006F.
|
|
Harmful in contact with skin
Only in: Household Cleaners
|
moderate
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
Harmful if inhaled
Only in: Household Cleaners
|
moderate
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
A U.S. Environmental Protection Agency review finds inhalation of 2-butoxyethanol causes hyperplasia of the stomach lining and bone marrow in lab animals.
|
moderate
|
U.S. Environmental Protection Agency. 2010. Toxicological Review of Ethylene Glycol Monobutyl Ether (EGBE) (CAS No. 111-76-2) In Support of Summary Information on the Integrated Risk Information System (IRIS). EPA/635/R-08/006F.
|
|
causes damage to organs
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
Causes central nervous system depression
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
confirmed animal carcinogen with unknown relevance to humans
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
|
A U.S. Environmental Protection Agency review finds inhalation of low levels of 2-butoxyethanol causes respiratory irritation in humans.
|
some
|
U.S. Environmental Protection Agency. 2010. Toxicological Review of Ethylene Glycol Monobutyl Ether (EGBE) (CAS No. 111-76-2) In Support of Summary Information on the Integrated Risk Information System (IRIS). EPA/635/R-08/006F.
|
|
May cause genetic defects
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
May cause cancer
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
Known to cause cancer
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
|
Known to cause reproductive toxicity (to females)
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
|
Known to cause reproductive toxicity (to males)
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
|
Known to cause reproductive toxicity
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
|
Carcinogenic to humans
|
some
|
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
|
|
Known To Be Human Carcinogen
|
some
|
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
|
|
Suspected of causing cancer
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
Known to cause cancer
|
some
|
California OEHHA (Office of Environmental Health Hazard Assessment): Proposition 65 List (2020 Update)
|
|
Harmful if swallowed
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
toxic if inhaled
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
Reasonably Anticipated To Be Human Carcinogen
|
some
|
National Toxicology Program (NTP): NTP 14th Report on Carcinogens
|
|
Toxic if inhaled
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
Causes skin irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
Causes respiratory irritation
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
upper respiratory tract irritation
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
|
Causes pulmonary edema
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
Causes skin corrosion
Only in: Oven Cleaner; Drain Opener/Clog Remover
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
Causes reproductive effects
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
Causes leukemia
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
Causes peritoneal cancer
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
cancer
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
|
central nervous system impairment
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
|
Asthmagen (irritation)
|
some
|
Association of Occupational and Environmental Clinics (AOEC): AOEC Exposure Code List (2020 Update)
|
|
Causes cancer
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
liver damage
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
|
Harmful in contact with skin
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
suspected human carcinogen
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
|
Possibly carcinogenic to humans
|
some
|
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
|
|
Causes skin irritation
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
Causes serious eye irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
confirmed animal carcinogen with unknown relevance to humans
|
some
|
American Conference of Governmental Industrial Hygienists (ACGIH): Threshold Limit Value (TLV) Basis
|
|
May cause respiratory irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
May cause respiratory irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
NTP Toxcast scored 1.5-2.5
|
some
|
National Toxicology Program (NTP): EWG Toxcast Analysis
|
|
Harmful if swallowed
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
Causes serious eye damage
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
Causes skin irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
Causes skin irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
Causes respiratory irritation
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
Causes respiratory irritation
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
Harmful if swallowed
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
Causes skin irritation
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
Causes eye corrosion
Only in: Drain Opener/Clog Remover; Oven Cleaner
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
Causes skin irritation
|
some
|
Centers for Disease Control and Prevention (CDC): NIOSH Pocket Guide to Chemical Hazards
|
|
causes serious eye irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
may cause respiratory irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
Causes serious eye irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
Causes serious eye irritation
Only in: Household Cleaners
|
some
|
EU GHS Hazard Labeling Codes: GHS Hazard Codes
|
|
Causes serious eye damage
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
Causes skin irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
causes serious eye irritation
Only in: Household Cleaners
|
some
|
European Chemicals Agency (ECHA): GHS Data from ECHA Website
|
|
Not classifiable as to its carcinogenicity to humans
|
low
|
International Agency for Research on Cancer (IARC): Agents classified by the IARC Monographs (through Volume 127)
|
|
Not known to cause asthma
|
low
|
Association of Occupational and Environmental Clinics (AOEC): AOEC Exposure Code List (2020 Update)
|
|
This substance is Generally Recognized as Safe (GRAS) as a food additive by the US Food and Drug Administration
Only in: Household Cleaners
|
low
|
U.S. Food and Drug Administration (FDA): FDA - Priority based Assessment of Food Additive (PAFA)
|
|
EPA testing shows this substance has low acute toxicity to aquatic life
|
low
|
Environmental Protection Agency (EPA): EPA Fathead Minnow Acute Toxicity Database
|
|
European Union Ecolabel program data shows this substance has moderate acute toxicity to aquatic life
Only in: Household Cleaners
|
low
|
EU Ecolabel: Detergents Ingredients Database
|
|
The European Union Ecolabel program reports this substance is readily biodegradable.
|
low
|
EU Ecolabel: Detergents Ingredients Database
|
|
A U.S. Environmental Protection Agency review suggests 2-butoxyethanol is not mutagenic.
|
low
|
U.S. Environmental Protection Agency. 2010. Toxicological Review of Ethylene Glycol Monobutyl Ether (EGBE) (CAS No. 111-76-2) In Support of Summary Information on the Integrated Risk Information System (IRIS). EPA/635/R-08/006F.
|
|
A U.S. Environmental Protection Agency review finds 2-butoxyethanol is not toxic to reproduction or development.
|
low
|
U.S. Environmental Protection Agency. 2010. Toxicological Review of Ethylene Glycol Monobutyl Ether (EGBE) (CAS No. 111-76-2) In Support of Summary Information on the Integrated Risk Information System (IRIS). EPA/635/R-08/006F.
|
