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C

COCAMIDOPROPYL BETAINE

 
Asthma/Respiratory
 
No Data, Some Concern
 
Skin Allergies &
Irritation
 
Some Concern
 
Developmental &
Reproductive Toxicity
 
No Data, Some Concern
 
Cancer
 
No Data, Some Concern
 
Environment
 
Some Concern
 
Top scoring factors: Low concern for biodegradation; damage to DNA; skin irritation/allergies/damage
COCAMIDOPROPYL BETAINE can be found in 88 products.
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Evidence

Health issue
 
Level of Concern
 
Source
The European Union Ecolabel program reports this substance is readily biodegradable.
 
low
 
Detergents Ingredients Database - EU Ecolabel
The European Union Ecolabel program reports this substance is anaerobically degradable.
 
low
 
Detergents Ingredients Database - EU Ecolabel
A Cosmetic Ingredient Review Expert Panel found that cocamidopropyl betaine did not cause genotoxicity in four studies.
 
low
 
Cosmetic Ingredient Review. 1991. Final Report on the Safety Assessment of Cocamidopropyl Betaine. International Journal of Toxicology 10(1), 33-52.
A review of industry studies finds alkyl betaines did not cause cell mutation in a standardized test.
 
low
 
Xavier Domingo. 1996. Betaines. New York: Marcel Dekker.
A Cosmetic Ingredient Review Expert Panel found that the lowest acute oral toxicity LD50 for cocamidopropyl betaine is 4,910 mg/kg body weight.
 
low
 
Cosmetic Ingredient Review. 1991. Final Report on the Safety Assessment of Cocamidopropyl Betaine. International Journal of Toxicology 10(1), 33-52.
A review of industry studies shows amidopropyl betaines have low dermal acute toxicity.
 
low
 
Xavier Domingo. 1996. Betaines. New York: Marcel Dekker.
A Cosmetic Ingredient Review Expert Panel found that cocoamidopropyl betaine is not a dermal sensitizer particularly at concentrations of 10 percent or less.
 
low
 
Cosmetic Ingredient Review. 1991. Final Report on the Safety Assessment of Cocamidopropyl Betaine. International Journal of Toxicology 10(1), 33-52.
A review of industry studies finds alkyl betaines have acute oral toxicity (LD50) as low as 1190 mg/kg.
 
some
 
Xavier Domingo. 1996. Betaines. New York: Marcel Dekker.
European Union Ecolabel program data shows this substance has high acute toxicity to aquatic life
 
some
 
Detergents Ingredients Database - EU Ecolabel
European Union Ecolabel program data shows this substance has high chronic toxicity to aquatic life
 
some
 
Detergents Ingredients Database - EU Ecolabel

Impurities

Health issue
 
Level of Concern
 
Source
Impurity: NITROSAMINES
NTP Toxcast scored 0.5-1.5
 
some
 
EWG Toxcast Analysis - National Toxicology Program (NTP)
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
NTP Toxcast scored 0.5-1.5
 
some
 
EWG Toxcast Analysis - National Toxicology Program (NTP)
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
Causes severe skin burns and eye damage
Only in: Drain Opener/Clog Remover; Oven Cleaner; Hard Water Stain Remover; Toilet Cleaner; Stove Top Cleaner; Household Cleaners
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
May cause an allergic skin reaction
Only in: Household Cleaners
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
Asthmagen
 
some
 
AOEC Asthmagen list - AOEC
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
Harmful if swallowed
Only in: Household Cleaners
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: NITROSAMINES
Reasonably Anticipated To Be Human Carcinogen
 
some
 
NTP 12th RoC - National Toxicology Program (NTP)
Impurity: NITROSAMINES
Probably carcinogenic to humans
 
some
 
EPA Integrated Risk Information System (IRIS) - Cancer - Environmental Protection Agency (EPA)
Impurity: NITROSAMINES
Probably carcinogenic to humans
 
some
 
IARC 103 - IARC
Impurity: 3-DIMETHYLAMINOPROPYLAMINE
Causes severe skin burns and eye damage
Only in: Oven Cleaner; Drain Opener/Clog Remover; Hard Water Stain Remover; Toilet Cleaner; Stove Top Cleaner; Household Cleaners
 
some
 
GHS Hazard Codes - EU GHS Hazard Labeling Codes
Impurity: NITROSAMINES
Known to cause cancer
 
some
 
Prop 65 - CA Proposition 65
 
 
About the ratings About the ratings
EWG provides information on cleaning product ingredients from the published scientific... continue reading →
EWG provides information on cleaning product ingredients from published scientific literature, to supplement incomplete data available from companies and the government. The ratings indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors that determine actual health risks, if any. (Hide)
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